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A COMPARATIVE STUDY TO ASSESS THE WELLBEING AND VIABILITY OF HYDRALAZINE PROFILE ALONG WITH GLYCERYL TRINITRATE AMONG FEMALES DIAGNOSED WITH SEVERE ECLAMPSIA & PRE-ECLAMPSIA

Dr. Muhammad Arslan Arshad, Dr Sadaf Aziz, Dr Zehra Hasnain

Abstract: Background: Hypertension amid pregnancy is a typical ailment around the world, happening in 12-22% everything being equal. In the created world, the occurrence of hypertension and the seriousness of its intricacies are diminished extraordinarily, due to the successful and broad antenatal consideration administrations. In any case, hypertension still stays one of driving reason for maternal horribleness and mortality in creating. Objectives: To think about the viability and wellbeing profile of hydralazine with glyceryl trinitrate (GTN) in ladies with extreme pre-eclampsia and eclampsia Patients and Method: This semi trial consider was directed in Jinnah Hospital, Lahore from February 2017 to March 2018. A total of 100 patients were incorporated into this investigation. 50 patients were given hydralazine and 50 patients got Nitroglycerine. Results: In groups A and B, the mean age was 26.8 ± 5.6and 25.4 ± 4.8, individually. In the two groups, the systolic and diastolic blood weights of patients were not essentially quite the same as one another. Meantime expected to accomplish powerful circulatory strain control in group A (hydralazine) was 31.0 ± 13.9 minutes and in group B (GTN) was 23.0 ± 20.3 minutes. Time interim between successful circulatory strain control and new hypertensive emergency was fundamentally drawn out in group A (96.1 ± 27.2 Vs 73.8 ± 18.1, P< 0.05) Conclusion: GTN sets aside less effort for powerful control of circulatory strain than hydralazine and wellbeing profile is practically identical with hydralazine Keywords: Severe Pre-Eclampsia, Eclampsia, Hydralazine, GTN.

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