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TITLE:

VARIOUS MODES OF CLINICAL PRESENTATION OF FALCIPARUM MALARIA

AUTHORS:

Dr Muhammad Tahir Mehmood, Dr Khadija Jamshaid, Dr Atif Sohail

ABSTRACT:

Abstract: Objective: The aim of this research work is to assess the various clinical presentations of malaria due to falciparum parasite. Study Design: This was a descriptive research work. Study Venue & Duration: This research work was conducted in Sheikh Zayed Medical College and Hospital Rahim Yar Khan and the duration of this research work was from September 2016 to January 2019. Methodology: Total of three hundred and forty-eight hospitalized patients with febrile illness were under screening for parasite of malaria with the peripheral smear of blood. We diagnosed the positive smears of 122 patients. Total 102 patients were positive for P. falciparum, who were the part of this research work. We found eleven patients positive for P. vivax & three patients found with combination of P. falciparum and P. vivax. These patients were not the part of this research work. We gave the injections of quinine sulphate to the patients who were ill critically, remaining patients got halofantrine and/or artemether through oral way. Results: There were total one hundred and eight patients who were positive in the blood smears. Among them 68.51% (n: 74) were male patients and 31.48 % (n: 34) were female patients. We diagnosed high temperature in all the patients. We observed jaundice in 36.11% (n: 39), nausea in 29.62% (n: 32), pain in the abdomen cavity in 21.29% (n: 23), changed condition of consciousness in 24.07% (n: 26) patients, diarrhea in 8.33% (n: 9), cough was present in 7.4% (n: 8) & seizures in 1.85% (n: 2) patients. Out of total one hundred and eight patients, 20.37% (n: 22) patients appeared with the malaria of cerebral, 7.4% patients were available with the infection of the respiratory tract, 8.33% (n: 9) patients appeared with gastroenteritis, 8.33% (n: 9) were present with acute pancreatitis but amylase of serum and ultrasound of the abdomen cavity omitted the discovery of the acute pancreatitis. Total 5.55% (n: 6) appeared with acute hepatitis & failure of fulminant hepatic with increased levels of serum ammonia in 3.70% (n: 4) patients and 2.77% (n: 3) patients appeared with the acute failure of kidneys. Conclusion: The occurrence of the malaria due to P. Falciparum was much high among the patients of this research work. There is a possibility of the prevalence of falciparum malaria in all the patients suffering from febrile illness even with different appearances of malaria. KEY WORDS: P. falciparum, P. vivax, appearance, prevalence, occurrence, methodology.

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