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OCCURRENCE OF HCV INFECTION AMONG PATIENTS SUFFERING FROM THALASSEMIA

Dr Umer Farooq, Dr Muhammad Asif Bashir, Muhammad Naeem Yousaf

Abstract: Objective: This research work aimed to find out the occurrence of infection of hepatitis C virus in the patients suffering from thalassemia in the south region of Punjab province, Pakistan. Methodology: This was a retroactive transverse case work conducted on two hundred a six patients suffering from thalassemia who got referrals to Jinnah Hospital, Lahore from the north regions of Punjab, Pakistan. This case work started in April 2017 & lasted up to May 2018. We gathered the data about demography of the patients from their files at hospital. The testing of samples of serum carried out with the help of anti-hepatitis C virus assays & nested-PCR method to evaluate the infection of HCV. Results: Among total two hundred and six patients, 47.10% (n: 97) patients were male and 52.90% (n: 109) patients were females. The average age of the patients was 16.40 ± 6.42 years. The total rate of occurrence of anti-hepatitis C virus was 28.10% (N: 58). Total 46 of positive anti-hepatitis C virus patients were also positive for RNA of HCV. The age of the patients with positive HCV was much high in comparison with the patients with negative HCV. The findings show that high occurrence of anti-hepatitis C virus or RNA of hepatitis C virus were available with a strong association with long transfusion period. Conclusion: It appears that the screening of the blood donors has reduced the infection of hepatitis C, utilizing the more precise procedure is very vital regarding the infections due to viruses and for the treatment of the patients of thalassemia with infection of hepatitis C virus more cautiously. Keywords: Occurrence, prevalence, thalassemia, HCV, infection, RNA, positive, comparison, evaluate, methodology.

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