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A REVIEW ON –FORMULATION AND IN-VITRO EVALUATION OF ORODISPERSIBLE TABLETS

Pramod Prakash Ronge* Dr. A.D. Shinde

Abstract: Recent advances in novel drug delivery (NDDS) aims to enhance the safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. Orodispersible tablet is advanced and convenient drug delivery system, now days acquiring the most widely accepted dosage form. The recent advance in NDDS aimed for the development of dosage forms convenient to manufacturing and administration, immediate release and increased bioavailability. Orally disintegrating tablets are solid dosage forms containing drug that disintegrate in the oral cavity within less than 1 minute leaving an easy-to-swallow residue. Orally disintegrating tablets is a good choice of drug delivery for pediatric and geriatric patients because difficulty in swallowing (Dysphasia). As our society is becoming increasingly age, there is need to development of an appropriate dosage form for the elderly patients are mostly desirable. The Advance development in oral disintegrating technology mainly works to improve the disintegration quality of dosage forms without affecting their integrity of dosage form. This article focuses on the available patented technologies and the advancements made so far in the field of fabrication of orodispersible tablets. Apart from the conventional methods of formulation, this review also provides the detailed concept of formulation, in-vitro evaluation and some unique technologies. Keywords: Orodispersible tablet, Dysphasia, Integrity, Patented technologies.

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