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ROLE OF HEPARIN IN WOUND HEALING IN 2ND DEGREE BURNS IN REMOTE AREA

Dr Usman Amiruddin, Dr Nazar Farid, Dr Fida Hussain, Dr Muhammad Hafeez ullah

Abstract: Heparin is a multifaceted compound with uses not only as an anticoagulant but also as an anti-inflammatory, anti-allergenic, anti-histaminic, anti-serotonin, anti-proteolytic and neo-angiogenic agent. The aim of the study was to study the effect of topical heparin in the management of second-degree burns. Between August, 2017 to February 2019. 60 consecutive patients, aged 10-60 years, 2nd degree thermal injuries ranging from 10% to 60%, were randomly enrolled in DHQ teaching hospital Dera Ghazi Khan (as area is remote and facilities are minimal) the study divided into a control group (C) and a heparin group (H) of 30 patients each. Patients treated with topical heparin experienced statistically significant improved pain relief, faster healing, fewer complications, and shorter hospital stays. The majority of the patients admitted was in an economically productive age group and were predominantly female. The distribution between the two groups according to age, type of burns and extent of burns was not statistically different. The current study demonstrates the efficacy of topical heparin in the treatment of 2nd-degree burns. Keywords: Heparin; Burns, Cost, Epidemiology.

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