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A COHORT SERIES TO ASSESS THE CORRELATION BETWEEN POOR OUTCOMES AND INCREASED HIGHER SENSITIVITY LEVELS OF TROPONIN T AFTER ACUTE ISCHEMIC STROKE

Dr. Faryal Ijaz, Dr. Arfa Azam, Dr Sania Mumtaz Tahir

Abstract: Background: In this study raised levels of higher sensitivity cardiac troponin T to happen within a substantial proportion of patients with severe ischemic stroke and can forecast poor mortality and result after stroke. Whether high levels of hs-cTnT can also forecast prognosis or hemorrhagic transformation in patients of ischemic stroke remains unclear. Objective: The study was conducted for the assessment of the association among poor outcomes with elevated high sensitivity troponin T after the acute ischemic stroke. Methods: This cohort research was carried out at Jinnah Hospital, Lahore from March 2017 to October 2017. A total number of 100 patients were enrolled in the study. For analysis of serum hs-cTnT level, blood samples were taken from all participants patients. the hospital duration of all patients was noted. the outcome was labeled as poor if the patient died in fifteen days after the admission. Results: Among 25 patients (25%) outcome was observed as poor. Among the Patients with raised Hs-TnT level 18 patients (36%) outcome was poor and among the patients with normal Hs-TnT levels only 8 patients (16%) outcome was poor. The relative risk of 1.602 indicated that patients with elevated Hs-TnT value were having 2.26 times more poor outcome chances as in comparison with the normal Hs-TnT level patients. This trend was the same in both genders, all age groups and within patients having a family history of MI. Conclusion: An elevated level of Hs-TnT is linked with the poor outcome within patients presenting with severe ischemic stroke. Keywords: High sensitivity troponin T, Poor outcome, Acute ischemic stroke

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