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PREGNANCY RELATED ACUTE KIDNEY INJURY

Muhammad Ali, Iqra Farooq, Ghulam Rasool

Abstract: Objective: To determine the frequency of pregnancy related acute kidney injury (PRAKI). Subject and Methods: This was a Case series study that was conducted at Sheikh Zayed Hospital Lahore, Jinnah Hospital, Lahore and THQ Hospital, Layyah from July to December 2018 in which pregnant females of age 20 to 40 were included. The RIFLE Criteria was used to label acute kidney injury. According to this criteria, acute kidney Injury was labeled as yes when there is two-fold increase in the serum creatinine, or GFR decrease by 50 percent, or urine output <0.5 mL/kg per hour for 12 hours. Results: In this study there were total 100 females with mean age of 31.42±4.48 years. There were 20 cases as primigravida and 80 cases with multigravida. PRAKI was seen in 24 (24%) of cases. PRAKI was seen higher in age group 31 to 40 years where it was seen in 18 (27.70%) of cases with p= 0.46. PRAKI was higher in multigravida as compared to primigravida where it was seen in 20 (25%) of 80 cases as compared to 4 (20%) of 20 cases in their respective groups with p= 0.88. Conclusion: PRAKI is common and is seen in every 4th case and it is more common in higher age groups and those with multigravida. Key Words: PRAKI, RIFLE, Pregnancy

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