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COMPARE THE INTENDED RESULT OF SINGLE BOLUS INTRAVENOUS LIGNOCAINE WITH MAGNESIUM SULPHATE TO REDUCE THE PRESSURE OF AVAILABILITY OF OXYGEN TO TISSUES DURING LARYNGOSCOPY AND INTUBATION

Dr Ayesha Zafar, Dr Monisa Tahir, Dr. Amera Aziz

Background: Placement of flexible plastic tube into trachea to maintain an open airway is done during general anesthesia and its effect availability of oxygen to tissue in patients. Objectives: The aim of this study was to compare the intended result of single bolus intravenous lignocaine with magnesium sulphate to reduce the pressure of availability of oxygen to tissues during laryngoscopy and intubation. Material and Methods: There were 178 patients included in this study. Two groups were made with 89 patients each. Group A receive intravenous 1% lignocaine 1mg/kg. Group B receive intravenous magnesium sulphate 10mg/kg. the data about mean arterial pressure, heart rate was compared between 2 groups. Data was analyzed wing SPSS version 22. Place of study. 1st March, 2018 to 31ST August, 2018 in Jinnah Hospital. Lahore. Duration of study: Time period for this study was 6 months. Result: In 54% patients of group A, 20% reduction of mean Arterial pressure was observed and 36.69% reduction in group B. there was 25% reduction in heart rate from basilines values in 11% patients of group A and 6.23% in that of group B. Conclusion: Comparative study showed that lignocaine was more effective than magnesium sulphate by preventing increase in HR and MAP after intubation and laryngoscopy. Keywords: Hemodynamic changes, MAP, HR, Stress response.

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