::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

DIFFERENT TYPES OF MANIFESTATIONS OF ANEMIA IN RHEUMATOID ARTHRITIS PATIENTS

AUTHORS:

Dr Omer Bin Naeem, Dr Mahnoor Furqan, Dr Muhammad Talha Bin Riaz

ABSTRACT:

Objectives: The basic aim of this study was assessment of anemia in rheumatoid arthritis patients, differentiated between the types of anemia and correlation between anemia and du ration of rheumatoid arthritis. Material and method: This cross-sectional study was conducted in ibne Sina hospital, Multan during January 2019 to November 2019. A total of 100 samples were obtained, among them 50 patients diagnosed with rheumatoid arthritis 50 samples were collected from healthy subjects as control. Fifty informed male and female consented patients diagnosed with Rheumatoid arthritis were recruited for the study. Rheumatoid arthritis Patients with chronic disease and such (renal failure, heart disease, liver disease, malignant diseases) were also excluded. Result: (60%) of rheumatoid arthritis are anemic and (40%) non-anemic the result demonstrated that the Hb level, RBCs and PCV are significantly reduced in anemic rheumatoid arthritis patients in comparison with non-anemic rheumatoid arthritis patients with P value (0.000) for Hb, RBCs and PCV. The result demonstrated also that MCH significantly reduced in anemic rheumatoid arthritis patients in comparison with non -anemic rheumatoid arthritis patients with P value (0.003) while MCV & MCHC are within normal range. In anemic rheumatoid arthritis patients, serum ferritin was significantly reduced in 7 while 23 patients have normal level of serum ferritin. Based on cutoff of 15μg/L for ferritin, 23% of anemic rheumatoid arthritis patients have IDA and 77% have ACD. Conclusion: There are two types of anemia in rheumatoid arthritis patients, IDA and ACD. ACD is more common in rheumatoid arthritis patients.