Dr Hamda Khurram, Dr Ramsha Khalid, Dr Mahnoor Ali
Lacrimal and salivary glands are exocrine tissues that have the main function of secreting tears and saliva, respectively. The main objective of the study is to analyse the proteins regulating salivary and lacrimal flow in xerostomia. This descriptive study was conducted in Punjab Dental Hospital, Lahore during March 2019 to December 2019. In this review analysis we explain the protein regulation salivary flow in xerostomia condition. Xerostomia and hyposalivation have been reported as common oral manifestations of diabetes mellitus (DM). Xerostomia in DM patients can be due to a number of reasons, such as damage to the salivary gland parenchyma, alteration in the microcirculation of gland, dehydration and disturbed glycemic control, but the exact cause is still unknown. It is concluded that Xerostomia occur due to defects in salivary and lacrimal fluid secretion can result in a multifacet degradation of patients’ quality of life.