::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RATE OF OCCURRENCE OF IMPAIRED FASTING GLUCOSE IN 1ST DEGREE RELATIVES OF THE PATIENTS SUFFERING FROM TYPE-2 DIABETES MELLITUS AND ITS CORRELATION WITH BMI

AUTHORS:

Dr Saad Ur Rehman, Dr Naveed Aslam, Dr Hafiz Muhammad Huzaifa Irfan

ABSTRACT:

Objectives: The aim of this study is to find out the rate of occurrence of impaired fasting glucose in the 1stdegree relatives of the patients suffering from Type-2 Diabetes Mellitus and its correlation with BMI (Body Mass Index). Methodology: This transverse research work was carried out at DHQ Hospitals, Sialkot from August 2019 to February 2020. People with ≥ 35 years of age, 1st degree relatives of the patients suffering from Type-2 diabetes mellitus, got recruitment in this research work and we checked their levels of fasting blood sugar 2 times a week apart. We divided the participants of this research work into three groups. Group-1comprised the persons with normal fasting blood glucose (FBS: <100.0mg/dl), Group-2 contained the patients with impaired fasting glucose (100.0-125.0 mg/dl), thought to be with high risk and Group-3 contained the patients who turned out to be present with frank diabetes (FBS: ≥126.0mg/dl). The patients with known diabetes mellitus and having pregnancy were not included in this research work. We used the Chi square method for the comparison of the proportions of levels of impaired fasting glucose versus body mass index. P value of <0.0010 considered as significant. Results: A sum of 100 patients were the participants of this study with average age of 44.27 years. 60.0% patients were present with normal fasting blood sugar, 31.0% patients appeared with impaired fasting blood sugar and 9% patients were present with frank diabetes (P <0.0010). There was a significant correlation between impaired fasting glucose and body mass index. There was increase in the rate of occurrence of impaired fasting glucose with the increase in body mass index. Conclusion: 1st degree relatives of persons suffering from Type-2 diabetes mellitus showed high rate of occurrence of impaired fasting glucose and most important risk factor was obesity. KEYWORDS: Fasting Glucose, Impaired, Body Mass Index, Type-2 Diabetes Mellitus, Pregnancy.