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TITLE:

COMPARISON OF RAISED LEVEL OF ANTI-THYROID PEROXIDASE ANTIBODY IN PATIENTS OF HYPOTHYROIDISM AND EUTHYROIDS

AUTHORS:

Dr. Muhammad Zafar Iqbal, Dr. Muhammad Haroon Bilal, Dr. Kehkshan Fatima

ABSTRACT:

Objective: To compare the frequency of raised level of anti-thyroid peroxidase antibody in patients of hypothyroidism and euthyroids. Material and methods: This case/control study was conducted at Department of Medicine, DG Khan Hospital, DG Khan from March 2019 to September 2019 over the period of 6 months. Frequency of raised level of anti-thyroid peroxidase antibody in patients of hypothyroidism and euthyroids was compared. Results: In present study, mean age of the cases was 32.42+10.09 years and mean age of controls is 32.45+10.12 years. Raised Anti-Thyroid Peroxidase Antibodies were found in 20 (28.99%) cases and in 5 (7.25%) controls. After applying chi-square test, statistically significant (P = 0.00) difference of Raised Anti-Thyroid Peroxidase Antibodies between cases and controls was detected. Conclusion: Results of present study showed higher rate of Raised Anti-Thyroid Peroxidase Antibodies in cases as compared to controls. Raised Anti-Thyroid Peroxidase Antibodies significantly associated with age and female gender. Keywords: Hypothyroidism, Euthyroids, Anti-thyroid peroxidase antibody

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