- CODEN : IAJPBB
- issn 2349-7750
TITLE:
FORMULATION AND EVALUATION OF EFFERVESCENT FLOATING TABLETS OF GLIPIZIDE
AUTHORS:
Korem Raju*, S. Madhuri, G. Srujana, S. Sindhuja, U. Swetha, Sara Sadaf
ABSTRACT:
The aim of the present research work was to develop a novel control drug delivery, to improve the solubility of poorly soluble drugs by effervescent technology. Six formulation of effervescent floating tablets of Glipizide were prepared by direct Compression method by using HPMC 100, Eudragit R400, ethyl cellulose as a polymers and sodium bicarbonate, citric acid as an effervescent mixture. They were subjected to Various pre and post compression evaluation parameters and results found to be within I.P limits. From all formulations F4 formulation shows controlled and complete release of drug over a period of 7 hours containing polymer as HPMC 100 and Eudragit Rc100 and shows 98.24% drug release. Key Words: Effervescent floating tablets, Glipizide, HPMC 100, Eudragit RL100, Ethyl cellulose
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
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S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
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