::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RATE OF OCCURRENCE OF ABRUPTIO PLACENTA AND ASSOCIATED FETO-MATERNAL OUTCOME

AUTHORS:

Dr Asad Waheed ul Zaman, Dr Usama Javed, Dr Saira Asghar

ABSTRACT:

Objective: This research work aimed to find out the rate of occurrence of abruptio placenta (AP) and associated feto-maternal outcomes in Jinnah Hospital, Lahore. Methodology: This prospective research work carried out at Department of Gynecology of Jinnah Hospital, Lahore for a duration of complete one year from January 2019 to December 2019. All the patients with confirmed diagnosis of AP and present with age of gestation of greater than twenty four weeks got inclusion in this research work. The collection of the information carried out on the well-organized questionnaire after taking the written consent from the patients. The analysis of the results carried out with the calculation of the variables in percentages. Results: Total amount of the females who gave birth in the duration of this research work was 2132. AP was present in 3.90% (n: 84) patients. Most of the females 51.10% (n: 43) were present in the age group of 25 to 30 years. The prevalence of this complication was high in multiparous females as 86.90% (n: 73). Seventy percent (n: 59) females were suffering from anemia. HTN (Hypertension) induced by pregnancy was present in 7.0% (n: 6) patients, DM (Diabetes Mellitus) in 6.0% (n: 5) patients and multiple pregnancy in 5.0% (n: 4) patients. There was presence of no risk factor in 12.0% (n: 10) females. With respect to delivery mode, 74.0% (n: 62) females delivered spontaneously through vagina and 25.0% (n: 21) females underwent CS (Cesarean Section). Only one patient met her death because of the severe state of anemia, shock and DIC (Disseminated Intra-vascular Coagulation). The most important maternal problem was hypovolumic shock in 25.0% (n: 21) patients, followed by hemorrhage after delivery in 13.0% (n: 11) patients, changed profile of coagulation in 7.0% (n: 6) patients and failure of kidneys in 2.30% (n: 2) patients. Total sixty two percent (n: 52) females gave birth to alive babies whereas there were thirty eight percent (n: 32) stillborn. Out of total fifty two alive babies, 2 infants died within seven days of birth because of prematurity. Overall rate of mortality of perinatal was 40.40%. Conclusion: AP has a strong association with high rate of feto-maternal morbidity as well as mortality. To decrease the incidence of this complication, there should be evaluation of the various risk factors of AP before and after the pregnancy period. KEY WORDS: AP, mortality, shock, complication, occurrence, association, coagulation, prematurity, kidneys, stillborn, hemorrhage.