Vaishnavi R. Shukla, Dr. Dhananjay M. Patil, Dr. Vinod A. Bairagi
A recent drug delivery technique is to inject the medication into systemic circulation at a defined rate using skin as the application site. The transdermal drug delivery route has attracted researchers because of the many related biomedical advantages. In addition to the formulations currently being developed, new medications are being designed using the transdermal system due to the current enormous advantage of this route of administration. It offers a non-invasive drug administration route, although its applications are restricted by low permeability to the skin. Transdermal drug delivery is one of the most promising methods of drug use. Medication delivery with transdermal patch systems exhibits slow, regulated release and absorption of drugs. The concentration of plasma drugs doesn't change significantly over time. Transdermal delivery system is a growing market that is expected to expand in the near future with the discovery of new applications and technologies for drug treatment. Transdermal delivery has many advantages over conventional drug administration, avoids hepatic first-pass metabolism, potentially reduces side effects, and improves patient compliance.Innovative research using penetration-enhancing strategies, such as iontophoresis, electroporation, microneedle and sonophoresis, is promising the successful use of these drugs as consumer-friendly, transdermal dosage forms in clinical practice. This review outlines the promising new technologies involved in improving transdermal permeation. Keywords: - Transdermal, Skin, Drug Delivery, Technologies.