- CODEN : IAJPBB
- issn 2349-7750
TITLE:
EFFICACY OF TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE (TDT) AS A DIAGNOSTIC MARKER IN ACUTE LYMPHOBLASTIC LEUKEMIA
AUTHORS:
Dr Nouman Shafique, Dr Muhammad Tehseen Ali, Dr Farhan Ghaffar Bhatti
ABSTRACT:
Aim: To differentiate Acute Lymphoblastic Leukemia from Acute Myeloid Leukemia and to Isolate Terminal deoxynucleotidyl transferase positive blasts in CSF. Place and Duration: In the Oncology department of Mayo Hospital Lahore for one year duration from March 2019 to March 2020. Methods: The study covered 35 persons. They were divided into three groups. They were elected from the Mayo Hospital, Lahore. 35 cases were divided into three groups: - Group A included 25 patients with acute lymphoblastic leukemia. Patients from group B 05 with acute myeloid leukemia and patients with a normal control group from group C 05 subjects. Results: Patients with Acute lymphoblastic leukaemia (Group A) had Terminal deoxynucleotidyl transferase positive blasts in peripheral blood smear while acute myeloid leukaemia (Group B) had no Tdt+ve Blasts in peripheral blood smear. Out of 25 patients of ALL, 06 (24%) patients of ALL had TdT positive blasts in Cerebrospinal Fluid Staining. Keywords: Terminal deoxynucleotidyl transferase (TDT), ALL, AML.
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Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
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S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
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