Dr Usman Waleed, Dr Muhammad Umair, Dr Abdul Manan
Aim: To determine diagnostic accuracy of film-screen mammography and ultrasound in differentiating benign from malignant breast masses taking histopathology as gold standard. Study design: A cross-sectional study. Place and Duration: In the Department of Radiology and pathology Jinnah Hospital Lahore for six months duration from September 2019 to February 2020. Subjects and methods: 210 patients were selected by non-probability purposive sampling with a palpable lump on the breast. Mammography was performed using cranio-caudal (CC) and medial-lateral oblique (MLO) projection. Ultrasound examination was performed using a 7.5 MHz linear transducer. The final diagnosis was based on a comparison of ultrasound and mammography results with biopsy results. Results: Mammography sensitivity and specificity was 77% and 94.9%, respectively. Positive and negative predictive values were 83.3% and 92.5%, respectively. The diagnostic accuracy ratio was 90.5%. The sensitivity and specificity of ultrasound were 77% and 96.2%, respectively. Positive and negative predictive values were 87% and 92.7%, respectively. The diagnostic accuracy ratio was 91.4%. Conclusion: Timely diagnosis and treatment of breast cancer is necessary. With early diagnosis, the probability of getting rid of breast cancer is over 90%. The study suggested that both mammography and ultrasound were comparable in terms of sensitivity and specificity. Keywords: mammography, ultrasound, breast cancer.