::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

EVALUATION OF LABORATORY PARAMETERS IN THE ESTIMATION OF THE REQUIREMENT FOR BACTEREMIA AND INTENSIVE CARE FOR PATIENTS SUFFERING FROM PYELONEPHRITIS AND GERIATRIC URINARY TRACT INFECTION

AUTHORS:

Dr Qamar Aslam, Dr Iram Imtiaz, Dr Sana Sajjad

ABSTRACT:

Objective: In this research work, we examined the geriatric patients detected with UTI (Urinary Tract Infection) and assessed the impacts of parameters as WBC (White Blood Cells), count of neutrophil, count of platelets, MPV (Mean Platelet Volume), RDW (Red-Cell Distribution Width), creatinine, total bilirubin, albumin, direct bilirubin, rate of erythrocyte sedimentation, CRP (C-reactive Protein) and ratio of neutrophil/lymphocyte for the estimation of the requirement for the bacteremia and IC (Intensive Care) for patients present with the pyelonephritis. Methodology: In the duration of this research work from January 2018 to December 2019, we evaluated 188 patients having 65 years of age or above retrospectively at the clinic for infectious diseases in Sheikh Zayed Hospital Rahim Yar Khan. Results: In this research work, 66.0% (n: 124) patients were males and 34.0% (n: 64) patients were females. The values of laboratory findings of the patients suffering from pyelonephritis & urosepsis were lower significantly in the Red-Cell Distribution Width bacteremia patients (P=0.0470). The values of laboratory during application of 3rdstep intensive care unit patients, who got treatment and discharge, were compared. There was significant low albumin in these patients, whereas AST, direct bilirubin and ALT were much high in those patients (P<0.050). Conclusions: All the patients, whose bio-chemical features have altered, particularly during their admission stay & follow up period, they should be assessed meticulously in terms of urosepsis, failure of multiple organs and need for intensive care. There are many diagnostic tests for the prediction of the requirement of intensive care and sepsis. However, many of these procedures cannot be in action in the conditions of emergency. It is great benefit that these laboratory parameters are accessible easily and these all parameters can be performed in the conditions of emergency. KEYWORDS: Urinary Tract Infection, Pyelonephritis, Mean Platelet Volume, Diagnostic, Intensive, Bio-Chemical, Geriatrics, Red-Cell Distribution Width.