::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A RANDOMIZED, CONTROLLED TRIAL OF TOTAL KNEE REPLACEMENT

AUTHORS:

Dr Waheed Sardar,Dr Zill e Rehman,Dr Aniqa Khan

ABSTRACT:

In United States, the number of total knee replacements has been increased drastically from 31.2 per 100,000 person-years. Approximately 670,000 total knee replacements were conducted in 2012 in United States only. With the increase of average age there is expected increase in the number of total knee replacements, which points toward future economic burden. The results of current study has shown that non-surgical treatment followed by total knee replacement therapy are more favorable as compared to nonsurgical treatment alone with pain killers and improving quality of life 12 months in patients with moderate-to-severe knee osteoarthritis who are eligible for unilateral total knee replacement. While total knee replacement is linked with a greater number of serious adverse problems and participants who were assigned to get nonsurgical treatment alone were not underwent total knee replacement before the 12-month follow-up and clinically well improvements.