Afnan Ullah Khan, Qaisar Nazeer Khattak, Wasim Khan
Introduction: Infective endocarditis is rare in children but potentially carries high mortality and morbidity. Aims and objectives: The main objective of the study is to analyse the early surgical therapy of infective endocarditis in children in Pakistan. Material and methods: This descriptive study was conducted in Khyber Teaching Hospital during June 2019 to January 2020. The data was collected from 100 patients of age range 10 to 15 years. Five ml of fasting fresh blood sample was taken from all the patients. Then this blood was centrifuged at 4000 rpm for 10 minutes. Results: The data was collected from 100 patients of both male and females. The mean age was 12.52±5.65 years. The mean values of serum ALP (203.92 U/I) and Ca (10.28 mg/dL) was higher in female subjects as compared to the male subjects. The noted in females and positive in male subjects. Significant correlation of CPK (p = 0.001) was found with age in females while positive correlation was found for CPK in both the groups with other variables. Conclusion: It is concluded that the association between dental procedures and the risk of IE remained insignificant after adjustment for antibiotic use, indicating that dental procedures did not increase the risk of IE.