Dr. Saba Asghar, Dr. Iqra Imdad, Dr. Tooba Bint E Shahid
Introduction and objectives: Early detection of diabetic nephropathy (DN) represents a great challenge in an attempt to reduce the burden of chronic kidney diseases in diabetic patients. The main objective of our study is the role of vitamin D at urinary level as a new biomarker in analysis of diabetic nephropathy. Methodology of the study: This cross-sectional study was conducted at Nishtar Hospital, Multan during June 2019 to January 2020. For the purpose of study 100 patients were selected and we collect the data from these selected patients. Furthermore, the analysis of Urine, creatine, Albumin and other series of test were taken place in the pathology laboratory of the hospital. Results: Vitamin D levels were significantly elevated in micro- and macroalbuminuria patient groups compared with those of the normoalbuminuric patient group and controls. There was significant correlation between serum and urinary levels of VDBP in total patient group. Conclusion: These investigations shall be helpful in assessing the biochemical alterations in the Pakistani diabetic population, which should contribute to the development of treatment plans for this disease which is one of the most widely occurring and debilitating diseases.