Dr. Hafiza Zubaria Shabbir, Dr. Sana Ashraf, Dr. Ayesha Akhter
Objectives: The main objective of our study is to find the role of antioxidants and measure the level of oxidative stress and their role in diabetic patients. Methodology: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2019 to November 2019. For this purpose we selected the patients who was suffering from a common disease diabetes. This study is based on the local population of Pakistan, which shows the stress level in Pakistani environment. Results: According to analysis of data level of antioxidant and oxidative stress is increasing in diabetic patients because cell become destroyed. GSH is important non-enzymatic antioxidant which helps in scavenging of free radical mechanism. Conclusion: It is concluded that level of antioxidants in our body plays an important role. It is obvious from the presented data that a relation exists between hyperglycaemia, oxidative stress, cellular and endothelial dysfunction.