- CODEN : IAJPBB
- issn 2349-7750
TITLE:
AN AUDIT OF HER-2/NEU RECEPTOR STATUS IN INVASIVE BREAST CANCER PATIENTS
AUTHORS:
Dr. Umair Ahmad, Dr. Mian Moeed Ahmad, Dr. Muhammad Zoha
ABSTRACT:
Objective: To find out the frequency of HER-2/Neu receptor status in invasive breast cancer patients. Material and methods: This cross-sectional study was conducted at Department of Surgery, Bahawal Victoria Hospital, Bahawalpur from January 2019 to June 2019 over the period of 6 months. Total 100 patients with breast cancer (having only lobular carcinoma / ductal carcinoma) as per operational definition and having age from 20-65 were selected. HER-2/Neu receptor status was assessed in selected patients. Results: In present study, mean age of the patients was 43.78±12.67 years. HER-2/Neu receptor was found positive in 40 (40%) patients and negative in 60 (60%) patients. Grade-I tumor was found in 21 (21%) patients followed by grad-II in 35 (35%) patients and grade-III tumor was found in 44 (44%) patients. Total 13 (13%) found with lobular carcinoma and 87 (87%) found with ductal carcinoma. ER was found positive in 75 (75%) patients and negative in 25 (25%) patients. PR was found in 65 (65%) patients and negative in 35% (35%) patients. Conclusion: Results of this study showed a higher rate of over expression of HER-2/Neu receptor. Most of the cases found with grade-III tumor. There was no association of HER-2/neu receptor status with age and obesity. In most of the patients, ER and PR was found positive. Key words: HER-2/neu, breast carcinoma, ER/PR, over-expression, co-expression
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
Cover Page
