v ::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::
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TITLE:

PERVASIVENESS OF ALCOHOL, SMOKING, AND ASSOCIATED COMORBID DISEASES IN PSORIASIS

AUTHORS:

Dr. Anam Riaz, Dr Ahad Sharif, Dr Zainab Hooria

ABSTRACT:

Introduction: Numerous studies suggest a relationship between smoking and alcohol. Psoriasis is associated with comorbidities such as diabetes, hypertension and metabolic syndromes that have a significant impact on severely affected patients. Aim: To investigate and assess smoking, alcohol and co-morbidities in patients with psoriasis. Place and duration: In the Dermatology department of Benazir Bhutto Hospital Rawalpindi for one year duration from January 2019 to January 2020. Patients and methods: The study included 100 patients with psoriasis who met the inclusion criteria. Detailed medical history and patient examination were conducted with particular attention to the onset, distribution and nature of psoriasis. The history of tobacco and alcohol use was studied, especially with the known history of other diseases. The diagnosis of psoriasis was clinical. Results: 58% of 104 patients were male and 42% were female. The average age was 34.8 + 14.71 years. Most patients had a generalized type of psoriasis. 26.9% of them smoked cigarettes. A history of alcohol consumption was found only in 2.9% of patients. The observed comorbidities accounted for 11.6% and 5.8% of hypertension and diabetes, respectively. 3.9% were positive for hepatitis C virus. Conclusion: In our study, smoking was associated with the severity of the disease, and average PASI scores were directly related to the number of years of packaging. Alcohol data are still scarce and more patients are needed to establish a relationship or refute. Concomitant diseases in psoriasis may require careful evaluation and early treatment. Key words: Psoriasis, smoking, alcohol, comorbidities.

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