1Saoud Tariq Etaiwi, 2 Dana Essam Asali, 3Abdulkareem Khalid S Bagar, 4Manar Hamad alqahtani, 5Bayan Mutlaq Almasoudi, 6Raghad Sulaiman H Alharazi, 7 Ehdaa Khalid Boudal, 8 Sumayyah Rudda Altalhi, 9Zainab Abdulmohsen Almuallem, 10Abdulaziz Ali Saeed Alshamlah
This review highlights the current understanding of dengue in children, including its clinical manifestations, diagnostic tests, management and prevention. We searched five databases (PubMed, EMBASE) to identify studies concerning dengue fever symptoms, and prevention in children published through, 2018. Dengue is accountable for considerable morbidity and death in children residing in tropical and subtropical regions and in kids visiting friends and family members living in these regions. Health problem can arise from infection with any of the 4 dengue virus serotypes and arrays from mild fever to possibly fatal dengue shock disorder. Babies with primary dengue infections whose mothers have some immunity versus dengue and youngsters that end up being infected with a 2nd dengue serotype after a preliminary primary dengue infection are at high threat for severe dengue. The widely accepted explanation for the development of severe illness is the antibody-dependent improvement design, which suggests that cross-reactive non-neutralizing antibodies increase viral infectivity. However, recent study into devices liable for the development of extreme dengue obstacle the antibody-dependent enhancement concept.