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Afaf Nasser Hakami , Amani Ali Madkhali, Batool Abed Ahmad, Lujain Abdulaziz Alrajhi , Ghaidaa Jamil Sindi , Amir Ahmad Khogeer, Norah Saad Alkahtani , Faten Saad Alkahtani , Malak Saleh Abdullah, Ola Adel Mohamed


Introduction: Acne vulgaris Is one of the most important inflammatory skin disease and it is the 8th most prevalent disease around the world with a prevalence that can reach 9% of the general population. It effects the teenagers in most cases and specially girls. However, it also can affect the adults. One of the worst complications of acne is the development of scars. As known, severe acne cause a very bad, long lasting scars that can cause psychological problems and social difficulties. Recently, the guidelines for acne treatment have become controversial. Aim of work: In this paper, we will review the most recent evidence on the management of acne vulgaris. Methodology: We did a systematic search for the current and recent advances in management of acne vulgaris using PubMed search engine ( and Google Scholar search engine ( Our search also looked for presentation, and treatment of acne vulgaris. All relevant studies were retrieved and discussed. We only included full articles. Conclusions: Acne is a chronic inflammatory disease that affects the adolescent population generally and girls specially, it can cause really serious psychological damage and physical scarring without the appropriate treatment. Depression, anxiety and even suicide are found in acne patients. The right early treatment is essential in acne, so in order to effectively and rapidly reduce acne lesions, and avoid scarring, a combination therapy of topical and systemic agents that targets as many of the underlying factors as possible should be considered. The emergence of P. acnes resistance requires a combination topical therapy and a low therapeutic threshold to introduce oral isotretinoin, which is a highly effective, well established treatment of acne and the only therapy that targets all of the etiological factors of this disease. Key words: Acne vulgaris, risk factors, clinical features, management


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