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PRIMARY PERITONITIS IN IMMUNOCOMPROMISED PATIENTS

1Dr. Nabeel Ahmed, 2Dr. Maaz Moin Khan, 3Dr. Muhammad Haris Rafiq,

This study is basically conducted to recognize the primary peritonitis in immunocompromised patients, for the purpose all patients admitted to the (ICU) intensive care unit of the Hospital from 1 January 2016 to 31 July 2017 with a diagnosis of primary peritonitis were retrospectively included. The medical record of the patients was gathered from the data recordings of the Department of Critical Care and Emergency and the Departments of Surgery. APACHE II (Acute Physiology and Chronic Health Evaluation II) was the main source in the calculation for every patient at the time of admission. Antimicrobial treatment management before and after the diagnosis of peritonitis was studied. According to the above-mentioned details of methods, 120 were included and the results concerning mortality, etiology of peritonitis and microbiological data were in accordance with previous studies. According to the APACHE II score (P = 0.005), age (P = 0.002), the existence of enterococcus in the peri-operative samples (which is defined P = 0.02) and the period between diagnosis and surgery (P = 0.04) were prognostic about the death within thirty days after peritonitis diagnosis. There was no prominent difference was shown in the mortality rate in patients whose post-operative antibiotic treatment was changed following results of intra-operative peritoneal cultures versus patients having inappropriate treatment (P = 0.96). The same observations were noted for anti-enterococcal treatment. This study concentrates on the importance of significant treatment of surgery and represents modern antibiotic treatment impact. The mortality and morbidity linked with the existence of enterococcus which basically not inspired by the treatment with an antibiotic would represent to advised the proinflammatory role of Enterococcus. Therefore, the studies of potential randomize are required to analyze the actual contribution ofthe contribution of enterococcal antibiotic coverage in this background.

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