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ANALYSIS OF MANAGEMENT OF ORAL ANTICOAGULATION THERAPY AFTER GASTROINTESTINAL BLEEDING: A TRANSLATIONAL STUDY

Adeel Mehmood, Firdous Saleem, Mariam Akram

Objectives of the study: The basic aim of the study is to explore and analyze the different management methods of oral anticoagulation therapy after gastrointestinal bleeding. Methodology of the study: This study was done basically by analyzing different management methods of oral anticoagulation therapies which were used after gastrointestinal bleeding. For this purpose we collected the data from different hospitals of Pakistan from different age groups for analyzing different oral anticoagulation techniques. The data was collected during 2018 from both genders. For data collection we visit the different hospitals and collect both demographical data and collect the views of patients after GIT bleeding. Then we further analyze this data by using MS excel and find the different values. Results: In critical patients who are actively bleeding with persistent or intermittent haemodynamic instability, coagulation factors should be administered even in the case of therapeutic ranges. If the patient is haemodynamically stable and/or responds sufficiently to resuscitation, it is advisable to simply observe the patient closely and defer endoscopy. Conclusion: We do not recommend bridging anticoagulation therapy in patients with low thromboembolic risk. Another issue is the timing of anticoagulant resumption in patients with clinically significant GI haemorrhage and no source of bleeding identified at endoscopy.

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