Muhammad Faisal Shahzad, Shoaib Jamil, Zainab Ejaz
Pakistani populations have one of the highest risks of coronary artery disease (CAD) in the world. Apart from smoking, women had more CAD risk factors (diabetes, hypertension, obesity, dyslipidaemia) than men. It is recognized that a better understanding of the topics is necessary for a meaningful communication between public, patients, and healthcare professionals. The aim of this paper will be to review the literature on the subject of CVD in women. The review will be in four sections, the first section will focus on contributions on mechanisms of pathophysiology, diagnosis, and treatment. In conclusion, this is the first large-scale population-based study from the Indo-Pakistan subcontinent, home to one-sixth of the world’s population, on gender differences in CAD and its determinants. Our findings indicate that one in four subjects aged ⩾40 years may have underlying CAD in urban Pakistan.