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TITLE:

VACCINES FOR LIFE STYLE DISEASES REVIEW

AUTHORS:

Julie John*, Silpa Sara Alex, Riya Alex, Irene Thomas, Ansa Mathew

ABSTRACT:

Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloi beta vaccine for Alzheimer’s disease represents a new concept in the field of vaccinations. This review highlights about the vaccines which are used for the life threatening life style diseases .Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines as preventive medicines. A number of therapeutic vaccines for cancer have been developed as novel immunotherapy. Their targets are usually specific antigens in cancer cells, allowing activated cytotoxic T cells (CTLs) to attach and remove the antigen-presenting cancer cells. Although treatment for these has been established for years based on different therapies reducing a series of risk factors, the degree of success has been only limited because of large side effects and non compliance.. In this sense, alternative treatments for lifestyle diseases have come into play where both innate and adaptive immunity have been produced through vaccination it is found to control the disease .Many experimental pre-clinical studies demonstrating proof of concept that vaccination using DNA and protein with an effective use of adjuvants and the optimal route of administration now provide a tangible new therapeutic approach that sets the stage for several of these vaccines to be tested in large, randomized, long-term clinical studies. A vaccine ready for human use will only be accomplished through the close association between academia regulatory government organizations and private industry, allowing the reality of a simple and successful therapy to reduce diseases and its severe clinical complications more over these vaccines posses greater advantages over the various drugs used for the treatment and many of the vaccines are showing promising results. KEY WORDS: life style vaccines-vaccines for cancer-types-approved vaccines-vaccines under clinical trials- antihypertensive vaccine-cholesterol vaccine – osteoporosis vaccines.

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