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FREQUENCY OF EARLY LEFT VENTRICULAR REMODELING AMONG THE PATIENTS WITH SEVER AORTIC REGURGITATION AFTER THE REPLACEMENT OF AORTIC VALVE

Dr Farhat Ullah Khan, Dr Farhana Rashid, Dr Waqas Azam

Objectives: The aim of this research work is to assess the rate of occurrence of early remodeling among patients of severe aortic regurgitation after the replacement of the aortic valve and to determine the prevalence of the in time remodeling among the patients having stroke volume of greater than 97.0 ml versus less than 97.0 ml before the replacement of aortic valve. Methodology: The design of this study was comparative study and the duration of this study was from July 2017 to November 2018 conducted in Lady Reading Hospital, Peshawar. There were total 57 patients with aortic regurgitation were the part of this research work. SPSS V.23 was in use for the statistical analysis of the collected information. T test was in use for the analysis of the different continuous variables and analysis of the qualitative variables carried out with the use of the Chi square test. Results: Among total 57 patients, early remodeling occurred in 59.6% (n: 34) patients after the surgical intervention. The average pre-surgical volume of stroke of the patient in whom there was occurrence of remodeling was 110.30 ± 9.66 ml whereas average pre-surgical volume of stroke of the patients who did not have to undergo remodeling was 86.650 ± 7.63 ml. Total 82.40% (n: 28) patients were present with the stroke volume of greater than 97.0 ml in whom there was occurrence of remodeling while among the patients present with stroke volume of less than 97.0 ml, there was occurrence of remodeling in only 17.60% (n: 6) patients. There was not a single mortality in the hospital. Conclusion: There is a strong relationship between the stroke volume and early remodeling of the left ventricular after the replacement of the aortic valve. The stroke volume greater than 97.0 ml is suitable predictor for the early remodeling of left ventricular. KEYWORDS: Left Ventricular, Aortic Valve, Remodeling, Replacement, Regurgitation, Mortality, Pre-Surgical.

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