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CAUSES OF INFECTED PANCREATIC NECROSIS AFTER SEVERE ACUTE PANCREATITIS

Hira Yaseen, Shafa Akram , Maryam Amin

Necrotizing pancreatitis is an inflammatory disease clinically changes from mild interstitial edema of the pancreas to extreme type of pancreatic necrosis and hemorrhage. Study design and setting: Descriptive case study; Surgical floor of Mayo Hospital, Lahore. Duration: It was a six months study Method: A total of 105 patients with age range 40-75 year were included using random sampling technique. Demographic history was obtained from the patients included in this study and patients were followed for 2-6 weeks with an abdominal CT scan to check for pancreatic necrosis and CT-guided fine-needle aspiration cytology [FNAC] to verify infection. The contributing factors such as gallstone, alcoholism, trauma, and malignancy were evaluated in every patient [both with and without infected pancreatic necrosis] as per surgical definition. The CT severity index was used to predict adverse outcome, such as mortality with pancreatic necrosis. Ranson scoring system was used to determine prognostic signs for clinical severity and rating of acute pancreatitis. Results: The bacterial culture was found positive in 37[35.2%] patients, gall stone was present in 41[39.0%] cases and choledocholithiasis was present in 30.5% patients. According to this study, the idiopathy was present in 36 [34.3%] cases and the infection was noted in 32[30.5%] cases. In conclusion, the prevalence of the infected acute pancreatitis was 30.5%. Keywords: Infection, severe acute pancreatitis, CT, Ranson, gall-stone, idiopathic.

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