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EFFECTIVENESS OF SUPPLEMENTATION OF VITAMIN-D IN THE PATIENTS SUFFERING FROM BRONCHIAL ASTHMA

Dr Sadaf Atta, Dr Muhammad Javed Afzal Chaudhry, Dr Pakiza Fatima

Objective: The deficiency of Vitamin-D has positive relationship with various complications of respiration system and bronchial asthma is one among those complications. The purpose of this research paper is to find out the effectiveness of supplementation of Vitamin-D in the patients suffering from the disease of bronchial asthma. Methodology: This is a cross sectional research work conducted in Nishter Hospital, Multan from July 2019 to September of 2019 in which we divided the 100 patients into two groups; Group-A and Group-B. There were 50 patients in each group. We gave the placebo to the patients of Group-A and we gave the dose of Vitamin-B of 50000 units every day through oral way. We followed the patients of both groups regarding improvement at first, second and third month of treatment. Results: We found no significant disparity in the patients of both groups regarding body mass index and asthma duration at the onset of this research work. The average pre-treatment level of Vitamin-D in the patients of Group-A was 14.230 ± 1.660 and of Group-B, the level was 15.3 ± 2.05 ng/dl. FEV-1 in the pre-treatment patients of Group-A was 64.350 ± 3.160 and of Group-B was 62.350 ± 2.160. We did not find any significant disparity regarding FEV-1 in the patients of both groups at first month. Whereas at second month, it was much greater in the patients of Group-B. At third months, the final consequence was present where the after treatment FEV-1 in the patients of Group-A was 66.130 ± 2.750 and in the patients of Group-B, it was 75.150 ± 2.040 with P-value of 0.0010. Conclusion: The supplementation of Vitamin-D improves the FEV-1 significantly at second months and these outcomes can be more significant if it is prolonged up to 90 days. KEYWORDS: Respiration, Asthma, average, prolonged, placebo, onset, FEV-1, Vitamin-D.

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