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TITLE:

DYSMENORRHEA OF ADOLESCENTS

AUTHORS:

Ivanov I.I, Popova-Petrosyan E.V., Lyashenko E.N., Dovgan A.A.

ABSTRACT:

According to modern scientific literature, up to 80% of women suffer from dysmenorrhea. At the same time, 10% of women every month lose the ability to work during these days. The most pronounced symptoms appear in adolescence. The aim of our study was to investigate the endocrine profile of female adolescents diagnosed with dysmenorrhea. Material and research methods. We analyzed 31 case reports of female adolescents who were treated in the children's clinical sanatorium “Zdravnitsa” in Yevpatoriya (Republic of Crimea), aged from 13 to 17 (average age 15.3 ± 2.2 y.o.) with dysmenorrhea, of whom 18 (58%) were adolescents and belonged to the age group 13-14 y.o., and 13 (42%) belonged to 15-17 y.o. Results and its discussion. When conducting a general clinical examination, dysmenorrhea was manifested by a headache, mood disturbance, nausea, and vomiting. Particular attention is drawn to the severity of pain in most of the studied patients. In the second age group, there is an aggravation of the dysmenorrhea symptoms. The concentration of estradiol in the blood serum of female adolescents of 13-14 years old is significantly lower by 0.14 ± 0.004 nmol / L compared with the control group. In girls aged 15-17, estradiol is reduced by 0.17 ± 0.004 nmol / L. In the first age group, the concentration of progesterone in the first phase is 2.7 times lower, in the second phase of the cycle it was 0.30 ± 0.02 nmol / L, which is 11.0 times lower compared to healthy peers (p <0.05 ) In female adolescents aged 15-17, the level of progesterone is 2.7 lower in the first phase and 11.6 in the second. Conclusion. In female adolescents with dysmenorrhea, the level of steroid hormones (estradiol, progesterone, testosterone) is low, the level of gonadotropic hormones is significantly lower in the second age group, with unchanged indicators of cortisol and prolactin. In the absence of timely treatment, the course of dysmenorrhea is aggravated, severe combined forms develop. Keywords. Teenagers, disorders menstrual cycle, dysmenorrhea.

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