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FREQUENCY AND RISK FACTOR OF BONE DISEASE IN PEDIATRIC INTESTINAL FAILURE

Dr. Noor Ahmed Shaikh

Objective: To determine the frequency and risk factor of bone disease in pediatric intestinal failure Patients And Methods: A total of fifty patients of intestinal failure were explored and included in the study. The cross-sectional survey includes 50 children diagnosed as intestinal failure either gender while the exclusion criteria were the parents who refused to give consent for the study. All the clinical parameters will be explored through history, physical examination and specific investigations as required. Dual-energy X-ray absorptiometry (DXA) scans were performed routinely and the lowest bone mineral density z-scores were recorded for each patient along with routine radiography whereas the frequency / percentages (%) and means ±SD compute d for study variables. Results: During six month study period total fifty children with intestinal failure were explored and study. The necrotizing enterocolitis was the most common underlying cause for intestinal failure. The mean ± SD for age (yrs) of population was 2.31±1.63. The BMD z-score ≤2.0 was identified in 30 (60%), vitamin D deficiency33 (66%), fractures 10 (20%) with male and female proportion as 35 (70%) and 15 (30%) Conclusion: Metabolic bone disorderrelated with pediatric intestinal failure puts countless these patients at a lifetime danger of bone cracks and osteoporosis. Keywords: Bone, Metabolic and Intestinal failure.

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