ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

USE OF TOLUIDINE BLUE FOR EARLY DIAGNOSIS OF ORAL CANCER

Dr. Muhammad Waleed Ghous, Dr Muhammad Mushhood Ur Rehman, Dr Sanabil Anwar

Background: One of the very common cancer in the whole world is oral cancer (OC) and its incidence depends upon the geographic regions. There is variation in the rate of the occurrence of this very cancer from very low in Japan to 43.0% in the country of Sir Lanka, India, Nepal & when compared with the cancers of other body parts. In our country Pakistan, oral cancer constitutes 8.0% malignant tumors standing next to the bronchogenic carcinoma in men and breast carcinoma in women. Better prognosis depends upon the early detection and in time treatment of this complication. Purpose: The purpose of this research prospective research work was to assess the use of the Toluidine Blue for the early identification of the oral cancer. Methodology: Patients suffering from oral abrasions with no clinical proof of the oral cancer, but appearing as non-curative oral ulcers greater than six months or increased margins were the parts of this research work. These patients were from age groups and from both genders. Toluidine Blue was in use for the staining of the abrasion and we took the biopsy from region under staining, in most of the patients from more than one single place. The selection of the patients carried out randomly. Results: Histopathological findings discovered the Squamous Cell Carcinoma in 10 patients and dysplasia in 3 patients. Conclusion: Toluidine Blue is useful as an aid for in time diagnosis of the oral cancer. Keywords: Oral Cancer, Toluidine Blue, Abrasions, Malignant, Carcinoma, Squamous Cell Carcinoma.

FULL TEXT