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CONSEQUENCE OF LITTLE QUANTITY INTRATHECAL CLONIDINE AS AN ADJUVANT TO HYPERBARIC BUPIVACAINE ON POSTOPERATIVELY ANALGESIA IN CASES OF EXPERIENCING ELECTIVE INFRA UMBILICAL OPERATIONS

Dr Raza Tariq, Dr Farooq Ahmed, Dr. Maryum Munir

Background: Clonidine, the imidazole imitative by α-2 adrenergic agonist deed, once exercised intrathecally gives decent analgesia also remains demanded to have negligible side effects as associated to opioids1. Researchers assessed belongings of little quantity intrathecal clonidine as an adjuvant to hyperbaric bupivacaine on postoperatively analgesia in cases experiencing elective infraumbilical operations. Methodology: Our current research was led at Services Hospital Lahore from April 2017 to March 2018. In the prospective, binary blind, randomized measured research, 70 cases experiencing elective infraumbilical operations remained arbitrarily separated into 2 sets of 35 every. Set-1 established 18 mg of 0.6% hyperbaric bupivacaine by 0.6 μg/kg clonidine also Set-2 established 18 mg of 0.6% hyperbaric bupivacaine by standard saline. The beginning of sensory hunk, period of motor obstruction, Visual Analog Score similarly time for initial rescue analgesia remained distinguished. Cases remained observed for any side effects. Results: Demographic outline of cases remained comparable in mutually sets. Set-1 had quicker beginning of sensory obstruction (p < 0.002) as associated to Set-2. Average period for 3 segment sensory equal reversion remained overdue in Set-1. Set-1 distinguished the continuation in period of analgesia i.e., 166.45 ± 24.15 minutes as associated to Set-2 anywhere release analgesia remained needed earlier. Conclusion: Intrathecal clonidine in the quantity of 0.6 μg/kg abbreviates beginning of sensory blockade, rises period of sensory obstruction also comprehensive motor salvage. Period of postoperatively analgesia remains pointedly protracted also period for prerequisite of release painlessness remains protracted deprived of producing substantial side effects if clonidine remains exercised in little quantities. Key words: Intrathecal; Clonidine; Operations, Infraumbilical

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