Dr Irfan Ali Tahir, Dr Hafsa Qazi, Dr Jehanzaib Zafar
Introduction: Cancer is becoming a leading cause of death in many countries of the world. Thyroid carcinoma is a relatively rare tumor, but represents the most frequent form of cancer of the endocrine glands. Objectives: The main objective of the study was to determine the frequency of thyroid carcinoma in multinodular goitre in patients undergoing thyroidectomy. Material and methods: This descriptive study was conducted in Holy Family hospital, Rawalpindi during 2019 to 2020. The data was collected from 50 patients of both genders. Patients with solitary nodule, Graves’ disease and metastatic lymphadenopathy with no palpable goitres were excluded from the study. Results: The data were collected from 50 patients of both genders. The female predominated the male in the ratio of 7.5:2.5. The most common presenting symptom was swelling in front of neck, which moved with swallowing. In 85(85%) patients the swelling which was of thyroid origin was benign, while in 15 (15%) patient it was malignant. Conclusion: It is concluded that the risk of malignancy in multinodular goitre is not as low as it was thought before and that it is quite significant and is mostly of the papillary type.