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TITLE:

RISK AND FREQUENCY OF HYPOGLYCEMIA IN SEVERE ACUTE MALNUTRITION IN PAKISTAN

AUTHORS:

Rashida Bibi, Rehana Nawaz, Tahira Shaheen

ABSTRACT:

Introduction: Both hypo and hyperglycemia occur frequently in sick children and have been associated with increased risk of deaths in pediatrics units. Objectives of the study: The main objective of the study was to analyse the risk and frequency of hypoglycemia in severe acute malnutrition among local population of Pakistan. Material and methods: This cross sectional study was conducted in Jinnah Hospital, Lahore during August 2019 to December 2019. This study was done with the permission of ethical committee of hospital. The data was collected from Pediatrics department of the hospital. The data was collected from those patients who visited the OPD of the hospital. All children having age range from 1 month—15 years were eligible for the study. Results: The data was collected from 200 patients. The mean age was 32.12±2.50 months. Of 200 children, 62.2% were severely ill, and 49.1% had at least one IMCI danger sign. A total of 15 had hypoglycemia, 99 low glycemia, 65 euglycemia and 21 hyperglycemia. Overall 149 (42.5%, 95% CI: 37.3–47.9) children presented with abnormal blood glucose. The distribution of blood glucose was skewed: median glycemia 5.2 mmol/L. Conclusion: It is concluded that Hypoglycemia and abnormal blood glucose are associated with a high risk of mortality for children. These results should encourage advocacy for improvements of local health facilities, especially pre-hospital care and management, which could impact the CFR.

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