::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ROLE OF TRANEXAMIC ACID IN PREVENTION OF SEROMA FORMATION AFTER HERNIOPLASTY

AUTHORS:

Dr Muhammad Adil Sohail, Dr Zainab Tariq, Dr Halima Tariq

ABSTRACT:

Introduction: Abdominal Hernia is defined as the bulging of part or whole of the contents of abdominal cavity through the weakened part of abdomen. Objectives: The main objective of the study is to analyse the role of tranexamic acid in prevention of seroma formation after hernioplasty. Material and methods: This cross sectional study was conducted in SIMS, Lahore during 2019 to 2020. The data was collected from 50 patients of hernioplasty. All the patients admitted from surgical OPD with the diagnosis of ventral abdominal hernia were included. Patients suffering from uncontrolled diabetes mellitus, cirrhosis, bleeding disorders and those with strangulated hernias were excluded. Results: The data was collected from 50 patients. In Group-1 (patients who received tranexamic acid postoperatively), out of 35-patients only 11-patients had total drain output of 300ml. In group-2 (patients who didn’t receive tranexamic acid), out of 35-patients, 12-patients had drain output between 150-300ml and 23 had drain output >300ml. Conclusion: It is concluded that Tranexamic acid reduces post-operative seroma formation in patients with ventral hernia repair after mesh hernioplasty. It also reduces the total time of drain removal after surgery.