::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE ANGIOGRAPHIC LIMITATIONS OF COGNITIVE OPTICAL TOMOGRAPHY IN THE RETINA, THE CHORIOCAPILLARIS BETWEEN CONTROL SUBJECTS AND DIABETIC PATIENTS WITHOUT DIABETIC RETINOPATHY

AUTHORS:

Dr Maham Yousaf, Dr Atta Ur Rehman, Dr Iqra Nawaz

ABSTRACT:

Aim: To examine the angiographic limitations of Cognitive Optical Tomography (COT) in the retina as well, the choriocapillaris between control subjects and diabetic patients without diabetic retinopathy (NDR). Relationships were concentrated between OCT angiographic limits, retinal structure limits and fundamental attributes in all subjects. Methods and Results: 69 patients were selected for the survey: control subjects (n ¼ 35) and NDR patients (n ¼ 26). The angiographic limits of the optical strength geology were: vessel thickness (%) (in the plexus of shallow and deep retinal vessels and in the choriocapillaris layer) and avascular zone of the fovea (FAZ) (mm2) in the plexus of shallow and deep retinal vessels of the Para fovea. Our current research was conducted at Services Hospital, Lahore from March 2019 to February 2020. Decor relating abundance angiography programming with fractional range angiography was used to evaluate vessel thickness and FAZ (device without flow region). The OCT of another zone was used to evaluate the thickness and volume of the complete retina, internal and external in the Para fovea. RESULTS. In the shallow and deep retina, vessel densities in the NDR (46.37% 6 13.32% and 31.03% 6 16.33%) decreased compared to control subjects (51.39% 6 13.05%, P ¼ 0.05; and 41.53% 6 14.08%, P < 0.03). The foveal avascular zone in the shallow retina of NDR patients (0.38 6 0.13 mm2 ) was greater than in controls (0.31 6 0.10 mm2 , P ¼ 0.02). The thickness of shallow vessels was fundamentally related to the thickness and volume of the complete retina in the Para-fovea (r ¼ 0.45, P ¼ 0.02; r ¼ 0.44, P ¼ 0.02) and to the external volume of the retina in the Para-fovea (r ¼ 0.36, P < 0.07) of solid subjects. Systolic circulatory stress and visual perfusion pressure essentially corresponded to the thickness of deep vessels in the NDR (r ¼ 0.45, P ¼ 0.02; r ¼ 0.46, P ¼ 0.01), but not in the controls. Conclusion: The shallow and deep retinal vessels of Para fovea in diabetic patients without diabetic retinopathy are both reduced, unlike in solid subjects. The relationship between vessel thickness, retinal tissue thickness, and clinical qualities of the subject contrasts between healthy subjects and patients with NDR. Keywords: Angiographic Limitations, Choriocapillaris, Diabetic, Non-Diabetic.