- CODEN : IAJPBB
- issn 2349-7750
TITLE:
RECENT ANTI-INFLAMMATORY AND IMMUNOMODULATORY DRUGS IN EPILEPSY
AUTHORS:
Ghadeer M Monshi, Nermeen A Awad, Rahmah H Alomiry, Mawadda O Fallatta1, Esraa G Khodari, Rawabi S Qadhi and Layla E Borham*
ABSTRACT:
Epilepsy is a neurological illness that is caused when nerve cells in the brain fire electrical impulses at a high rate that causes a sort of electrical storm in the brain, known as a seizure. A repeated episode of seizure is known as epilepsy. Mostly epilepsy is caused by infection, illnesses, head injuries, brain tumors and lead poisoning. At least one-third of epileptic patients have seizures that cannot be controlled with the traditional anti-epileptic medications. Inflammatory reaction that releases neuromodulator molecules and inflammatory mediators that are involved in the pathophysiology of seizures can stimulate epilepsy. In this review we highlighted most promising components to control the epilepsy cases. It is concluded that anti-inflammatory and immunomodulatory drugs have a positive role to decrease the bouts of epilepsy and limit it. They can be effective in improving the outcomes of patients with refractory epilepsy and status epilepticus as per the published studies. Keywords: Epilepsy, Drugs, Anti-inflammatory, Immunomodulatory
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NLM ID:101711216 [Serial]
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ICV 2015 - 61.16
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