Dr. Rabbia Shahzadi, Dr. Natasha Wafa, Dr. Faiza Maqsood, Dr. Saiqa Ilyas, Dr. Khurram Khaliq Bhinder
Introduction: The CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in the lung and in antigen-presenting cells such as M2 macrophages and dendritic cells, which can act as a chemoattractant for both lymphocytes and immature dendritic cells. Objectives: The main objective of the study is to analyse the serum CCL 18 levels in women with polycystic ovarian syndrome. Material and methods: This cross sectional study was conducted in Sir Gangaram Hospital, Lahore during June 2019 to March 2020. The data was collected from 90 female patients which was suffering from PCOS. The data was collected into two groups, one was control group and one was selected patients. Results: The data was collected from 90 patients. 45 patients in group A and 45 patients in group B. The mean age was 25.4±5.67 years. The mean serum CCL 18 levels in the PCOS group were 28.32 ± 4.17 ng/mL with the levels in the control group being 11.90 ± 4.91 ng/mL. Conclusion: It is concluded that serum CCL 18 were considered to be the basic marker for PCOS. There is also a significant difference in serum CCL 18 levels in PCOS subjects with age and BMI matched healthy controls.