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TITLE:

ESTIMATION OF NADOLOL AND BENDROFLUMETHIAZIDE IN API AND ITS DOSAGE FORM BY RP HPLC

AUTHORS:

Mr Mohammod Yakub Pasha, Dr. T. Mangilal

ABSTRACT:

We have developed a simple, general, and reliable HPLC Method and validation for the simultaneous estimation of nadolol and bendroflumethiazide drugs according to (ICH) guidelines. Nadolol and bendroflumethiazide peaks have been observed at a retention time of 1.757, and 3.208 minutes, respectively, and they have kept 5 minutes as a total run time. As per linearity results, the average correlation coefficient of nadolol and bendroflumethiazide is 0.999 which indicates they have good linearity, robustness, and stability. Keywords: LC-MS/MS, RP-HPLC, Nadolol, Bendroflumethiazide.

FULL TEXT DOWNLOAD LINK: http://iajps.com/pdf/november2020/205.IAJPS205112020.pdf


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