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TITLE:

TO DETERMINE THE INCIDENCE OF HELICOBACTOR PYLORI INFECTION IN PATIENTS OF DIGESTIVE SYNDROME

AUTHORS:

Dr Zaryab Mirza, Dr Ayesha Sohail, Dr Hira Bint Abdul Jabbar

ABSTRACT:

Background: Dyspepsia is defined as a group of symptoms localized to the upper abdomen such as pain, discomfort, postprandial fullness, bloating, early satiation, epigastric burning, belching, nausea, and vomiting. The aim of this study was to determine the frequency of Helicobactor pylori infection in patients presenting with dyspepsia. Study Design: Descriptive cross-sectional study. Place and Duration of study: This study was conducted at the Services Hospital Lahore for one year from June 2019 to June 2020. Materials and methods: Total 165 patients including both male and female > 15 years with symptoms of dyspepsia for > 4 weeks were recruited. All the patients who used proton pump inhibitors in last two weeks or antibiotics in last four weeks were excluded from the study. All patients with decompensated liver cirrhosis, gallstones, hypothyroidism, gastric surgeries and gastrointestinal malignancies were also excluded. After getting informed written consent, detailed history and physical examination, H- pylori stool antigen test was used to determine the frequency of h pylori infection. Results: One hundred and sixty-five patients having dyspepsia were included in this study.37% were male and 63% were female. Mean age of the population was 41.4 + 17.9 with a minimum age of 15 years and maximum 85 years. The most common complaints of the patients were epigastric pain and fullness. The prevalence of Helicobactor pylori in the population studied was 56.4%. The prevalence of H- pylori was 63.9% in male and 51.9% in female. Conclusion: Prevalence of h pylori is very high, hence need proper investigation and treatment. Key Words: Dyspepsia, Helicobactor pylori, Prevalence, Stool antigen test.

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