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TITLE:

ACUTE KIDNEY INJURY IN THE CRITICALLY ILL PATIENT: A REVIEW STUDY

AUTHORS:

Dr Saman Sardar, Dr Faiza Sirbuland,Dr Rais Nawaz.

ABSTRACT:

Objective: A comprehensive review of the literature to provide a focused and thorough update on the issue of acute kidney injury (AKI) in the surgical patient. Methods: A PubMed and Medline search was performed and keywords included AKI, renal failure, critically ill patients. Findings: A common clinical problem encountered in critically ill patients is AKI. The recent consensus definitions for the diagnosis and classification of AKI (i.e., Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease/Acute Kidney Injury Network) have enabled us to standardize the severity of AKI and facilitate strategies for prevention. These strategies as well as treatment modalities of AKI are discussed. We provide a concise overview of the issue of renal failure. Conclusions: Acute kidney injury is a common problem in the critically ill patient and is associated with worse clinical outcomes. A standardized definition and staging system has led to improved diagnosis and understanding of the pathophysiology of AKI. There are many trials leading to improved prevention and management of the disease. Key words: Acute kidney injury, renal failure, critically ill, renal replacement therapy.

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