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ANALYSIS OF ROLE OF PLASMA OBESTATIN LEVELS IN OBESITY WITH RELATION TO DAILY LIFE STYLE IN PAKISTANI POPULATION

Muhammad Adil Nawaz, Khalida Qasim, Muhammad Adnan Sarwar

Introduction: Obesity is a pathological condition, which results from an imbalance between caloric intake and expenditure, and is characterized by excessive body fat accumulation, that has severe impact on life quality and life expectance due to the burden of associated co-morbidities. Aims of the study: The main aim of the present study is to analyze the role of plasma obestatin levels in obesity which is associated with daily life style in Pakistani population. Methodology of the study: This cross sectional study was conducted in RHU Centre Tibbi Qaisrani District Dera Ghazi Khan during 2018 to 2019. The data was collected from 100 obese patients which was also suffering from heart and cholesterol diseases. Results: Mean fasting obestatin levels was 0.450 ± 0.468 and 0.959 ± 0.889 respectively in normal and obese and the difference of mean fasting obestatin levels between the both groups was statistically significant with p value 0.000. Conclusion: Obestatin plays very important role in obesity and it is directly correlated with blood glucose level.

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