ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

AN ANALYTICAL STUDY TO ASSESS ASSOCIATION OF SEVERITY OF CORONARY ARTERY DISEASE AND DIABETIC RETINOPATHY

AUTHORS:

Dr Muhammad Daniyal, Dr Hira Khalid, Dr Saba Anjum

ABSTRACT:

Objectives: We aimed in this analysis to verify the relationship among severity of Coronary Artery Disease (CAD) and Diabetic Retinopathy (DR) and to assess the association of stage of severity of CAD with DR. Study design: It was a cross-sectional type of analysis. Place and Duration: This study was conducted in Holy Family and Benazir Bhutto Hospital Rawalpindi for the duration of one year from March 2018 to February 2019. Methodology: Diabetic Mellitus cases who were suffering from this disease for more than a duration of 5 years which were tested through coronary angiography (CA) were selected for this analysis. The total patients were examined through fundoscopy and were classified into proliferative-DR, pre-proliferative-DR and N0-DR. Coronary angiography was carried out to evaluate the severity of Coronary Artery Disease (CAD) and patients were classified as severe CAD, moderate, mild and none depending upon the number of veins taking part or left main stem (LMS) ailment. The association among CAD and DR was concluded through chi-square test and prevalence odds ratios (POR) were evaluated through logistic regression model. Results: A number of 166 patients having average age of 55.5 ± 8.8 years were included in this study out of which number of male patients was 79, number of NO DR cases was 35, pre-proliferative DR cases were 110 and number of 21 patients had proliferative-DR whereas number of 63 patients had mild CAD, no of 50 patients were having moderate CAD and 18 patients had severe CAD. The relationship among severity of CAD and diabetic retinopathy (DR) was evaluated as 86.68 where the value of p was 0.000 through chi-square test. PORs for severity of coronary artery disease (CAD) by raising stage of DR were observed as usually raised from 0.27 times for no-DR to 4.27 times for pre-proliferative-DR and for proliferative-DR 6.33 times after managing different consequent influences. Conclusion: It was concluded through our study that Diabetic Retinopathy (DR) is just not highly related to Coronary artery disease but a most severe CAD raising the odds of CAD by 2.27 times detected at higher stage of retinopathy. Keywords: Diabetes Mellitus, Diabetic Retinopathy, Coronary Artery Disease

FULL TEXT

Top
  • Follows us on
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.