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TITLE:

PREMENOPAUSAL AND POSTMENOPAUSAL EFFECTS ON BONE MINERAL DENSITY

AUTHORS:

Dr. Saba Anjum, Dr. Hira Khalid, Dr. Syed Hassaan Ahmed Bokhari

ABSTRACT:

Objective: To determine the premenopausal and postmenopausal effects on bone mineral density in women to detect osteopenia and osteoporosis in these women. Study design: A Cross-sectional study. Place and duration of the study: In the Physiology Department of Holy Family Hospital Rawalpindi for a duration of one year, from May 2018 to May 2019. Methods: 34 premenopausal and 33 postmenopausal women were sampled and their bone mineral densities were determined using the DXL calscan heel densitometer. The weight and height of each individual were determined to gauge the body mass index (BMI). To determine the variation between the two groups, a t-test was performed, and Pearson's correlation coefficient was used to determine the correlation between the two groups. Results: In postmenopausal women, Bone mineral density (T score) was significantly lower than in premenopausal women (p = 0.000). Osteopenia was present in 70.59% of premenopausal women and 63.64% of postmenopausal women and osteoporosis was present in 30.30% of postmenopausal women. There was a static negative correlation (p = 0.0016) between bone mineral density and age in postmenopausal women. Conclusion: Bone mineral density decreased significantly in postmenopausal women and this density decreased with age. More than two thirds of premenopausal and postmenopausal women were found to demonstrate osteopenia, while 30% of postmenopausal women were osteoporotic. Key words: T score, bone mineral density (BMD), osteoporosis, osteopenia.

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