ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

NAFLD: PREVALANCE AND ASSOCIATED COMPLICATIONS AMONG PREGNANT FEMALES

FAWAD IQBAL JANJUA, JAMSHID SIDDIQUE, SADIA KHAN

Non‐alcoholic liver disease (NAFLD) is the common form of chronic Liver disease (CLD), and its worldwide prevalence continues to extend with the growing epidemic. The aim of this study is to assess prevalence of NAFLD and risks of adverse physiological state and delivery outcomes in females diagnosed with NAFLD before delivery compared to population controls. A cross sectional analytical study was done from 1st May, 2019 to 5th September, 2019 in DHQ hospital, Gujranwala. 361 Women carrying a singleton pregnancy admitted for delivery were considered to the study. Data was collected with self-administered questionnaire. During the study period 59(16.3%) females were diagnosed with NAFLD prior to delivery. Grade I and II were same (i.e 40.7%) whereas Grade III NAFLD was among 18.6% of pregnant females. Maternal education, age and gender of the baby was insignificantly associated with NAFLD (p-value>0.05), whereas body mass index, pre-existing diabetes miletus and hypertension, pregnancy induced hypertension, pre-eclampsia, apgar score, low birth weight and gestational age was significantly associated with NAFLD (p-value<0.05). Positive and significant correlation has been observed among ALTs and ASTs with NAFLD Grades (p-value<0.05). NAFLD is the common problem during pregnancy and is significantly associated with pregnancy complications such as PIH, pre-eclampsia, LBW, gestational age and apgar score. Mean ALTs and ASTs level increased with the increase in the Grades of NAFLD from Grade I to III.

FULL TEXT